One Million DNA Changes

• Analyzing one million DNA changes, we identify your genetic risks for heart attack, stroke, hypertension, diabetes, bad cholesterol (LDL), good cholesterol (HDL), and triglycerides.

• This report is is customized for different ethnic groups, such as Asians, Caucasians, and people of mixed race.

Proteomic Test - Detect 7000 proteins simultaneously

• Predict stroke and heart attack within 4 years.

• Predict early lung cancer.

• Predict dementia within the next 5 to 20 years.

• Understand how serious is your pre-diabetes by checking fatty liver, blood sugar issues, kidney health, and belly fat around organs.

• Determine if you have chronic kidney disease.

• Track how well treatments are working by keeping an eye on important health signs from your brain, lungs, heart, kidneys, liver, and other main body systems.

Genetic health traits are variations in our DNA that influence us to choose diets, exercise, foods in particular ways.

Diet and Exercise - Understand your DNA may help you live healthier by improving your nutrition, diet, exercise patterns, food choices.

Weight Loss - Knowing how your DNA may affect obesity and food preferences

DNA insights may help you lose weight more effectively.

Numerous clinical guidelines, policy statements and cohort studies support the use clinical-grade whole genome sequencing as a first tier test to

• Achieve the highest diagnostic yield

• End diagnostic odyssey

  Contact us to obtain clinical guidelines, policy statements and large scale cohort study publications appropriate to you clinical specialty.

We use multiple molecular diagnostic technologies to determine difficult-to-detect mutations. By using these technologies, we achieve industry leading diagnostic yield - We return a pathogenic finding in 60%-75% of patients.

Technologies used:

• Deep whole genome sequencing at 40x-80x

• RNA sequencing

• Long read sequencing

• CNV analysis

• Repeat expansion analysis

• Clinical microarray

• Pharmacogenomics

• Proteomics

Whole Genome Sequencing Test is appropriate for the following indications

• Autism spectrum disorder

• Pediatric disorders with complex symptoms

• Familial cardiomyopathy, arrhythmia

• Hereditary cancers

• Epilepsy, eye, immune system, neurological and movement disorders

• Alzheimer’s disease, dementia and Parkinson’s disease

• Adult unexplained diseases

• Pediatric undiagnosed disorders

• Rare diseases

• A genome is an organism’s complete set of DNA, including all of its genes. Each genome contains all of the information needed to build and maintain that organism.

• A human genome contains more than 3 billion DNA base pairs, including more than 20,000 genes.

Genes

• Genes provide instructions for making the proteins our bodies are built of.

Areas Between Genes

• The areas between genes are called introns. These regions make up about 99% of the human genome. Introns can help switch genes on and off at the right times.

• Genetic variations in the intronic regions are known to be associated with many common disease risks, such as our predisposition for lung and liver cancers, heart attack, stroke and diabetes.

Rainbow whole genome sequencing test covers all 20,000 genes and the remaining 99% of DNA, providing you the most comprehensive diagnosis, disease prevention and health improvement insights.

Rainbow Genomics’ whole genome sequencing tests provide a detailed analysis of:

20,000 genes and the spaces between them (introns), represented by 3 billion DNA letters.

Hard-to-detect, disease-related genetic changes linked to complex neurological and psychiatric disorders, like autism.

• Many gene mutations are hard to detect because they involve challenging mutations such as structural changes, mosaic mutations.

• Exome or multi-gene panel sequencing might miss these variants.

• Whole genome sequencing at 40x-80x resolution gives us high enough detail and consistent coverage to detect these tricky mutations, leading to accurate disease diagnosis.

• This helps us achieve industry-leading diagnostic success rates.

• 40X-80X Deep Whole Genome Sequencing: 120-240 Gb

• Whole genome sequencing produces over 10 times more data compared to data generated from whole exome sequencing

Unlike many labs that test one thing at a time, we use multiple technologies at once to find various gene mutations, blood protein changes, giving us one of the highest success rates.

We use all these: 20,000 genes + 7000 blood proteins + 3 billion DNA codes from your genome.

These tests find genetic variations linked to hereditary and common disorders.

Healthy people, especially those with family members diagnosed with hereditary disorders (like breast cancer), may benefit from these tests.

A positive result can help individuals and their doctors create better plans for prevention and early detection.

• You may have symptoms that don’t clearly show what disease you have, making diagnosis hard.

• Your physician may suspect that a “disease-causing genetic change” is responsible for your disorder.

• Analysis of your genetic information can quickly lead to a final diagnosis.

• With a diagnosis, your doctor can suggest a treatment or ways to reduce risk based on how the disease might develop.

We analyze 1-2 million changes in your DNA and 7000 blood proteins to determine your long-term risk for serious diseases (heart attack, stroke, diabetes, etc.) and how likely you are to get these diseases in the next few years.

Our doctors will provide personalized care to prevent or treat these diseases, leading to better health outcomes.

• Genetic counselors inform patients about how a genetic condition might affect them or their families.

• Skilled genetic counselors also provide psychosocial support to help patients and their families adapt to their genetic test results and genetic conditions.

• Genetic counselors also refer patients to other healthcare providers, advocacy and support groups.

• Rainbow Genomics provides genetic counselling services delivered by internationally-accredited genetic counselors (U.S. or Australia) -

  • Licensed, Board-Certified or Board-Eligible with multiple years of clinical training and experience